The Dynamic Phantom is a customized product specifically designed to assess the spatial, depth resolution and absorption or fluorescence sensitivity of a device.
Developed by the biomedical optics community, which includes leading experts in Near-Infrared Spectroscopy, its purpose is to mimic dynamic changes and provide a performance assessment of the system in terms of depth, absorption sensitivity, and spatial resolution. An adapted version of the phantom is available to simulate dynamic fluorescence or Raman signals.
Why choose dynamic phantom
- Robustness and ease of use: Designed for quick routine applications in clinical settings, our Dynamic Phantom ensures
robustness and user-friendly operation, facilitating seamless integration into your daily clinical practices.
- Durability and reproducibility: Experience consistent reference points during clinical studies with the durability
and reproducibility of our phantom, ensuring reliable results for your research endeavors.
- Versatility across instruments: Adaptability is key, and our phantom excels by offering a general-purpose tool applicable
to different instruments. Regardless of the clinical problem at hand, our Dynamic Phantom stands ready for widespread use.
- Simulating absorption changes: Tailored to simulate localized changes in the absorption coefficient, our switchable phantom is ideal for a spectrum of applications, including brain functional imaging, detection and characterization of breast tumors, and monitoring tumor reduction post-neoadjuvant chemotherapy.
Explore the realm of dynamic imaging possibilities with our revolutionary Dynamic Phantom. In the domain of diffuse optics, our innovative phantom takes center stage, offering a noninvasive tool for investigating highly scattering media, such as biological tissues in the NIRS range
KEY FEATURES
Two-part design
Comprising a homogeneous host phantom and a movable slab with a cylindrical inclusion, our phantom allows dynamic switching, enhancing its versatility in various imaging scenarios.
Switching capability
Effortlessly transition from a homogeneous to an inhomogeneous phantom by moving the slab, providing the flexibility needed for diverse clinical applications, to simulate tumor or dynamic changes in tissues.
Applicability across technologies
While initially designed with near-infrared spectroscopy in mind, our Dynamic Phantom extends its capabilities to characterize other modalities like fluorescence or Raman by incorporating fluorophore or Raman active inclusion, ensuring testing capabilities across a spectrum of technologies.
TECHNICAL SPECIFICATIONS
- Main block dimension: 110 x 70 x 50 mm (length x width x height) (configurable)
- Slider dimension*: 140 x 30 x 10.5 mm (length x width x height) (configurable)
- Inclusion dimension: cylinder (10 x 10 mm, diameter x height)
- Slider/Inclusion depth from surface: 5 mm (configurable)
- Main block, slider optical properties @780 nm:
Absorption (μ a) – 0.2 cm -1
Reduced scattering (μ s’) – 10 cm -1
- Inclusion optical properties: μ a – 0.05 – 0.4 cm -1 (configurable)
μ s’ – 10 cm -1 (configurable)
- Inclusion fluorescence properties (optional): ICG mimic
* multiple depth and spatially distributed inclusions in a single slider are possible for depth and spatial resolution test.
Unlock the understanding of dynamic changes in your clinical research with our Dynamic Phantom, enabling new methodologies and standards for algorithm development, calibration, quality control and beyond!
This product has been developed thanks to the results achieved from a group of world major experts in NIRS diffuse optics, as reported in the following paper:
Antonio Pifferi, Alessandro Torricelli, Rinaldo Cubeddu, Giovanna Quarto, Rebecca Re, Sanathana K. V. Sekar, Lorenzo Spinelli, Andrea Farina, Fabrizio Martelli, Heidrun Wabnitz, “Mechanically switchable solid inhomogeneous phantom for performance tests in diffuse imaging and spectroscopy,” J. Biomed. Opt. 20(12) 121304 (28 July 2015) https://doi.org/10.1117/1.JBO.20.12.121304
APPLICATIONS
Unleashing the potential of Dynamic phantom
Functional Brain Imaging: Seamlessly switch between homogeneous and inhomogeneous states to simulate absorption changes, offering a valuable tool for advancing functional brain imaging studies.
Breast Tumor Detection and Characterization: Mimic localized changes in absorption properties, providing a realistic simulation for detecting and characterizing breast tumors with precision.
Tumor Reduction Monitoring: Evaluate tumor reduction after neoadjuvant chemotherapy with confidence, using our Dynamic Phantom to simulate absorption variations in a clinical context.
Fluorescence guided surgery: Seamlessly switch between homogeneous and inhomogeneous states to simulate fluorescence changes, offering a valuable tool for advancing fluorescence guided surgical studies.
Testing capabilities across different technologies: Diffuse Reflectance, spatial frequency domain imaging, functional near infrared spectroscopy, fluorescence guided surgery, Raman guided surgery.