The 16 half MEDPHOT Matrix is a product including 16 phantoms inspired by the well known MEDPHOT protocol.
Experience the power of precision in biophotonics instruments evaluation with the 16 half MEDPHOT phantoms. These meticulously designed and rigorously tested phantoms lie at the heart of the MEDPHOT protocol, revolutionizing the way photon migration based systems are characterized and validated.
MEDPHOT phantoms serve as the indispensable link between theory and practice, providing a tangible and controlled medium to assess instrument performance. Crafted with exceptional attention to detail, these phantoms replicate the optical properties of real biological tissues, offering a realistic and reproducible testing environment.
The kit includes cylindrical or square solid optical phantoms with varying optical properties.
Why choose the 16 half MEDPHOT matrix
- Scientific Rigor: Built on the foundation of scientific excellence, each phantom undergoes rigorous validation, ensuring that it meets the stringent criteria
of the MEDPHOT protocol.
- Realistic Simulation: 16 half MEDPHOT matrix phantoms faithfully replicate the optical behavior of human tissues, providing a lifelike testing scenario
for biophotonics instruments.
- Standardization: Embrace a standardized approach to instrument evaluation by incorporating the 16 half MEDPHOT phantom kit into your testing regimen. Achieve
consistent and comparable results across instruments and laboratories.
- Versatility: Designed to accommodate a diverse range of instruments and applications, our phantoms offer unmatched versatility in performance assessment.
- Reliability: Trust in the reproducibility and accuracy of your instrument evaluations. The 16 half MEDPHOT matrix phantoms aim at being the gold standard for reliability, instilling confidence and credibility in your measurement outcomes.
APPLICATIONS
Neuroscience Research: Investigate brain oximetry and neuronal activity with precision, enabling advancements in understanding neural processes and disorders. The accuracy of the MEDPHOT protocol can be validated against concurrent measurements from MRI scans, confirming the protocol’s ability to reliably detect changes in regional oxygenation.
Dermatology: Gain insights into skin tissue properties and enhance optical diagnostic and therapeutical tools development for dermatological conditions, paving the way for non-invasive assessments and therapies.
Sports Science: Explore muscle oxygenation and metabolic changes during physical activities, contributing to the optimization of athlete performance and training strategies.
Clinical environment: Elevate the reliability of medical diagnostic instruments by rigorously testing optical methods for applications like optical mammography and other near-infrared tissue spectroscopy techniques.
Biomedical research: Drive breakthroughs in various biomedical research areas, from the study of bone and joint diseases to the characterization of photosensitizers for molecular imaging.
Quality assessment: Ensure the quality and consistency of agricultural products and pharmaceutical tablets using non-destructive optical methods, safeguarding product integrity.
Elevate your research, development, and quality assurance endeavors with the 16 half MEDPHOT phantoms. Join the forefront of biophotonics instrument evaluation and ensure your instruments are primed for excellence. Discover precision like never before – explore the MEDPHOT phantoms today!
WHAT IS THE MEDPHOT PROTOCOL
The MEDPHOT protocol is a cutting-edge methodology designed for the comprehensive evaluation of photon migration instruments. Developed within the European Thematic Network MEDPHOT, this protocol addresses the critical need for standardized testing and characterization of photon migration instruments, which play a pivotal role in a wide range of biomedical applications.
Photon migration, a rapidly evolving field over the past decade, holds immense promise in various medical domains, from optical mammography to brain oximetry, tissue spectroscopy, and beyond. As diverse as these applications are, they share a common foundation – the physics of photon migration. This shared groundwork enabled the development of a unified protocol that can be used to assess and characterize a diverse array of systems based on different types of techniques (like frequency or time domain, space resolved, etc.).
This protocol involves 32 phantoms with a wide range of optical properties typically found in human tissues. By focusing on measurement results rather than hardware specifications, the protocol sets out to provide a standardized framework that bridges the gap between various biophotonics setups and techniques.
The MEDPHOT protocol enables a cohesive approach to instrument assessment with wide-ranging benefits:
- Quality Assurance: ensures consistent and reliable instrument performance during routine use, especially in critical clinical trials.
- Innovation Support: facilitates the development of new instruments and the enhancement of existing ones by quantifying the impact of technical changes on measurement outcomes.
- Comparison and Benchmarking: offers a common basis for comparing different instruments and their measurement results, promoting transparency and reliability across the field.
The 5 assays of MEDPHOT protocol
The MEDPHOT protocol encompasses 5 critical criteria (assays) that ensure the reliability and precision of measurements: accuracy, linearity, noise, stability, and reproducibility.
1. Accuracy: The accuracy assay evaluates how closely the measurements match the true values. By comparing measured data with established reference standards, researchers can quantify the level of agreement between the two. For instance, in a brain oxygenation study, NIRS measurements of oxygen saturation can be compared with invasive measurements from catheters placed directly in blood vessels to assess the accuracy of the NIRS system.
2. Linearity: Linearity assesses how well the system maintains consistent measurements across a range of concentrations. By employing samples with varying concentrations of target molecules (such as oxygenated and deoxygenated hemoglobin), researchers can gauge whether the measurements exhibit a linear response. This is crucial to ensure that the device accurately reflects changes in tissue properties.
3. Noise: The noise assay examines the background interference or random fluctuations in acquired signals. By measuring signals in the absence of any sample, researchers can determine the inherent noise level in the system. Lower noise levels enhance the system’s sensitivity to subtle changes in tissue characteristics, allowing for more reliable measurements.
4. Stability: Stability testing evaluates the system’s robustness over time. By repeatedly measuring a stable sample over an extended period, researchers can identify any drift or changes in the system’s performance. This assessment ensures that the NIRS device maintains its accuracy and consistency throughout extended experiments or clinical sessions.
5. Reproducibility: Reproducibility gauges how consistent the NIRS measurements are when repeated under similar conditions. This is achieved by performing multiple measurements on the same sample or different samples with identical properties. High reproducibility ensures that results can be confidently replicated by different researchers and across various settings.
